Description
Pal-GHK Peptide
Palmitoyl-GHK, also known as palmitoyl-tripeptide-1, is a synthetic hybrid molecule consisting of a three-amino-acid sequence (Gly-His-Lys) attached to a palmitic acid chain. The addition of the palmitoyl (fatty acid) group is thought to enhance penetration through the stratum corneum (outer skin layer) by increasing lipophilicity and potentially aiding passage through lipid-rich skin barriers.
Researchers suggest that Pal-GHK may stimulate collagen production in the skin’s extracellular matrix because the GHK tripeptide sequence is released during collagen breakdown in tissue repair models and may act as a signal to fibroblasts — cells responsible for producing collagen and other structural proteins.
Pal-GHK may also exhibit antioxidant potential by neutralizing free radicals, which are unstable molecules that can damage cell structures and contribute to cellular aging and inflammation.
Chemical Makeup
Molecular formula: C30H54N6O5
Molecular weight: 578.8 g/mol
Other Known Titles: Palmitoyl Tripeptide-1, Palmitoyl oligopeptide, Biopeptide-CL
Research and Clinical Studies
Collagen Synthesis
Research published in scientific journals suggests that GHK-related sequences may stimulate collagen synthesis and production of other extracellular matrix proteins like elastin and glycosaminoglycans in lab settings. One study observed that peptides with structural similarity to GHK may act as feedback signals in tissue repair, helping promote collagen synthesis and extracellular matrix organization.
Wrinkle Depth and Skin Texture
Clinical research mentioned in product summaries suggests that Pal-GHK applied in topical formulations may be associated with reductions in wrinkle depth, length, and surface roughness in controlled trials. Improvements in overall skin texture were noted compared to baseline or placebo groups.
Antioxidation
Laboratory studies indicate that GHK-based peptides may exhibit antioxidative effects by reducing signals from reactive oxygen species like hydroxyl and peroxyl radicals, potentially helping protect cells from oxidative stress and contributing to improved skin integrity and resilience.
Pal-GHK peptide is available for research and laboratory purposes only. Please review and adhere to the site’s Terms and Conditions before ordering.
