Description
Matrixyl
Matrixyl, also known as palmitoyl pentapeptide‑4 (formerly palmitoyl pentapeptide‑3), is a synthetic peptide currently under scientific investigation for its potential to stimulate collagen production in the skin. It is classified as a matrikine — a messenger peptide that may regulate cell activities by interacting with specific receptors. Collagen is a structural protein considered important for flexibility and integrity in the skin’s extracellular matrix. The conjugation with a palmitoyl group may offer improved delivery across the skin and enhanced stability against skin proteases.
Chemical Makeup
Molecular formula: C₃₉H₇₅N₇O₁₀
Molecular weight: 802.05 g/mol
Other known titles: Palmitoyl pentapeptide‑4, palmitoyl pentapeptide‑3
Research and Clinical Studies
Matrixyl Peptide and Collagen Synthesis
Studies suggest that Matrixyl may act as a signal peptide fragment of the C‑terminal propeptide of type I collagen, potentially signaling fibroblasts to stimulate feedback regulation of new collagen synthesis and extracellular matrix (ECM) proteins. Fibroblasts are cells found in connective tissue that play a key role in forming and maintaining the ECM scaffolding of tissues.
Matrixyl Peptide and Wrinkles
Several studies report that Matrixyl may influence fibroblasts and collagen synthesis, with some research models showing reduced wrinkle depth and improved skin surface texture compared to placebo in controlled settings.
Matrixyl Peptide and Tissue Repair
Experimental work suggests Matrixyl may positively impact wound healing in laboratory models, with increased healing compared to control groups.
Matrixyl peptide is available for research and laboratory purposes only. Please review and adhere to our Terms and Conditions before ordering.
