Description
Receptor Grade IGF-1 LR3 (1MG) – Research Peptide
Receptor Grade IGF-1 LR3 (1MG) is a high-purity, laboratory-grade synthetic peptide derived from Insulin-Like Growth Factor-1 (IGF-1). Engineered through advanced peptide and genetic modification techniques, this compound is designed specifically for controlled scientific and in-vitro research applications.
IGF-1 LR3, also known as Long Arg3 IGF-1, features a modified structure that includes an additional 13 amino acids at the N-terminus and a substitution of arginine at position three. This results in an 83-amino-acid peptide compared to the 70 amino acids of native IGF-1. These modifications are believed to reduce binding affinity to IGF-binding proteins (IGFBPs), potentially increasing its availability for receptor interaction in laboratory environments.
Developed under strict quality-controlled conditions, Receptor Grade IGF-1 LR3 ensures high consistency, purity, and reliability for advanced biochemical and analytical research.
Overview
IGF proteins are studied for their interaction with IGF-1 receptors, playing a role in cellular signaling pathways. IGF-1 LR3’s modified structure is believed to reduce interaction with IGF-binding proteins, potentially allowing for increased receptor engagement in controlled research settings.
Experimental studies in laboratory models have explored the peptide’s potential influence on cellular growth signaling, with some findings suggesting enhanced activity compared to native IGF-1 under specific conditions.
Chemical Makeup
Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
Molecular Weight: 9117.5 g/mol
Other Known Titles: Long-(Arg3) insulin-like growth factor-I, Insulin-like growth factor long chain R3
Research and Experimental Studies
Anabolic Signaling and Tissue Growth
Preclinical and in-vitro research has investigated the potential of IGF-1 LR3 to influence cellular protein synthesis and growth-related signaling pathways under controlled laboratory conditions.
Glucose Uptake and Metabolic Activity
Certain studies suggest that IGF-related peptides may play a role in glucose uptake and metabolic signaling pathways such as PI3K/Akt and AMPK, though these findings remain limited to experimental research environments.
Muscle-Related Research
Laboratory studies have explored how IGF-1 analogs like LR3 may impact cellular markers associated with muscle protein dynamics, including regulatory pathways involved in growth and differentiation.
Product Specifications
Product Name: IGF-1 LR3
Strength: 1MG
Purity: ≥99%
Form: Lyophilized (freeze-dried) powder
Manufacturing Origin: USA
Quality Control: Independently tested with COA
Key Features
High-purity receptor-grade research peptide
Structurally modified IGF-1 analog (Long Arg3 variant)
Reduced binding to IGF-binding proteins (IGFBPs)
Suitable for advanced biochemical and cellular research
Consistent batch quality with verified testing
Secure and sterile packaging
Important Notice
This product is strictly intended for laboratory research purposes only.
Not for human or animal consumption, medical use, diagnostic use, or therapeutic application.
Handle and store according to standard laboratory safety protocols.
